The London General Omnibus Company was founded in 1855 to amalgamate and regulate the many independent horse-drawn omnibus services then operating in London. Originally an Anglo-French enterprise, also known as the Compagnie Generale des Omnibus de Londres, the LGOC soon became the largest omnibus operator in London.

It bought out hundreds of independently-owned buses and established a consistent level of service for its fleet.

Within a year, the LGOC controlled 600 of London's 810 omnibuses.

LGOC began using motor omnibuses in 1902, and the last LGOC horse-drawn bus ran on 25 October 1911. In 1908 the LGOC bought the Road Car Company, the Vanguard Company, and its other main rivals, thereby gaining a virtual monopoly in London.

The merger of these three companies (the Road Car Company was also known as Union Jack owing to its habit of flying the British flag on its vehicles) gave the new and enlarged LGOC the most experienced operating and engineering personnel of any operator - and perhaps manufacturer - in the country at the time.

In 1912, the Underground Group, which owned most of the London Underground, bought the LGOC. In 1933, the LGOC, along with the rest of the Underground Group, became part of the new London Passenger Transport Board. The name London General fell into disuse, and London Transport instead became synonymous with the red London bus.