Cambridge Heath Road was originally Cambridge Road.
The North Metropolitan Tramways Co. opened a route along Grove Road to Old Ford Road in 1872 but closed it in 1873 when it opened routes along the old turnpike roads from Mile End along Cambridge Road to Stamford Hill, and along Hackney Road.
In 1893 the Cambridge Road route was called the Museum line, along which red trams ran from Aldgate. The London County Council ran electric trams over the existing routealong Cambridge Road from 1910.
By 1930 buses ran on the same routes as trams. The Empress Omnibus garage was built at Cambridge Heath in 1925. In 1939 the London Passenger Transport Board introduced trolleybuses along Cambridge Road.
