The district around Pember Road remained completely rural until about 1850.
Kensal Green manor house, which was roughly situated where Wakeman Road joins the Harrow Road, was pulled down in the 1860s.
From about 1860 the lands to the west of Kilburn High Road began to be built upon and in the 1870s the sale of Banisters Farm led to the building of many present day streets.
By 1880, the rapid build up of the area caused official concern. Many houses had no regular sewers and privies drained into old, broken down pipes.
During the Second World War, Pember Road was the location for a aggregate night time bomb which fell during the Blitz.